Table 1.
Occurrence of henipavirus-induced syncytia in vitro. A “+” indicates that syncytia were observed, and a “–” that syncytia were not observed, following either live infection (“live”) or viral glycoprotein transfection (“transf.”); blank cells indicate that no data are available; non-exhaustive list. There are no data from KuV and MojV live infection experiments as these viruses have not been isolated but sequenced only [39,71].
| Cell Line | HeV | NiV | CedV | KuV | MojV | References | |||
|---|---|---|---|---|---|---|---|---|---|
| live | transf. | live | transf. | live | transf. | transf. | transf. | ||
| Vero (epithelial) | + | + | + | + | + | + | - | + | [20,79,80] |
| HEK293T (epithelial) | + | + | + | + | + | [20,79] | |||
| A549 (epithelial) | + | + | + | + | + | [70,79] | |||
| Raji B (lymphoblast) | - | [20] | |||||||
| PK13 (epithelial) | – | - | [20,31] | ||||||
| BHK (fibroblast) | + | + | + | + | + | + | – | + | [79,80] |
| CHO (epithelial) | – | – | – | – | [48,50,79] | ||||
| L2 (epithelial) | + | + | + | [79] | |||||
| Rat2 (fibroblast) | + | + | + | [79] | |||||
| EidNi (epithelial) | + | [80] | |||||||
| NHBE (epithelial) | + | + | [81] | ||||||
| SAEC (epithelial) | + | + | [81] | ||||||
| hOE (epithelial) | + | + | [82] | ||||||
| HMVEC (endothelial) | + | [20] | |||||||
Vero: monkey renal epithelial cells; HEK293T: human renal epithelial cells; A549: human pulmonary epithelial cells; Raji B: human lymphoblast cells; PK13: porcine renal epithelial cells; BHK: baby hamster fibroblasts; CHO: Chinese hamster ovary epithelial cells; L2: rat pulmonary epithelial cells; Rat2: rat fibroblast; EidNi: Eidolon bat renal epithelial cells; NHBE: human bronchi epithelial cells; SAEC: human small airway epithelial cells; hOE: human olfactory epithelial cells; HMVEC: human microvascular endothelial cells.