Table 2.
Restriction critical residues in sequenced wild mouse Fv1 genes.
| Fv1 Sites | ||||||
|---|---|---|---|---|---|---|
| Fv1 Type 1 | Subspecies, Name (Location) | 270 | 352 | 358 | 399 | C-Terminus 2 |
| n or n-like | domesticus, SK/Cam (UK) | S | K | V | n | |
| domesticus, CalWM (USA) | K | S | K | V | n | |
| musculus, PWK (Czech Republic) | K | S | K | V | n | |
| musculus, SKIVE (Denmark) | K | S | K | V | n | |
| nr or nr-like | musculus, (Novobirsk, Russia) | F | K | V | n | |
| musculus, CZII (Slovakia) | K | F | K | V | n | |
| spp., Aks (China) | K | F | K | V | n | |
| spp., Las (China) | K | F | K | V | n | |
| spp., (Vladivostok, Russia) | K | F | K | V | n | |
| domesticus, ZALENDE (Switzerland | F | K | V | n | ||
| domesticus, CLA (USA) | F | K | V | n | ||
| d-like | domesticus, PRAE (Morocco) | Q | S | K | V | n |
| b or b-like | molossinus, MOM (Japan) | K | S | E | R | b |
| bactrianus, (Iran) | S | K | V | b | ||
| castaneus, (Philippines) | S | K | V | b | ||
| castaneus, H12 (India) 5 | K/Q 3 | S | K | V | b/b2 3 | |
| castaneus, H30,34 (India) 5 | K/Q 3 | S | K | V | b3 | |
| castaneus, H15,27 (India) 5 | K/R 3 | S | K | V | b | |
| castaneus, H24,26,28,36 (India) 5 | K | S | K | V | b | |
| molossinus, MOLD (Japan) | K | S | K | R | b | |
| molossinus, MOLC (Japan) | K | F | K | R | b | |
| molossinus, MAE (Japan) | K | F | K | R | b | |
| molossinus, JF1/Ms (Japanese fancy mouse) | K | F | K | R | b | |
| molossinus, (Saitama, Japan) | F | K | R | b | ||
| spp., IAS3 (Korea) | F | K | R | b | ||
| spp., Wuh (China) | S | K | R | b | ||
| domesticus LEWES (USA) | Q | S | K | V | b3 | |
| castaneus, CAST/EiJ (Thailand) | Q | S | K | V | b4 | |
| castaneus, H14 (India) 5 | Q | - 4 | - 4 | - 4 | - 4 | |
1 Based on C-terminus for b, 352 for n and nr, 270 for d. 2 C-terminus types: n, ELSLKPTAATKL; b, ELSLKPTAAGLTSVGSVGVLSLSPWKHQSNS; b2, ELSLKPTAAGLTAGLAPVGSVGVLSLSPWKHQSNS; b3, ELRGQR; b4, ELSLKPTAAGLPAGLASVGSVGVLSLSPWHKH. 3 Heterozygous. 4 Stop gain variant at position 327 (TGG > TAG) in both H14 alleles, resulting in predicted protein truncation or lack of expression of the corresponding allele. This variant has the b2 C-terminus. 5 The ten Fv1b-like castaneus H genes are identical to Fv1b except where indicated and a 137T/S substitution in H34.