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. 2021 Aug 31;13(9):1734. doi: 10.3390/v13091734

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© 2021 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).

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Principal coordinate analysis of RapidAIM cultures from each donor reveals that BAFASAL^® treatment has minimal impact on microbial composition. RapidAIM assays from each donor were analyzed separately using principal coordinate analysis of the Bray–Curtis dissimilarity and plotted as separate panels. This analysis reveals the large impact that FOS treatment has on patient microbiotas that could be obscured by high interpatient variability (Figure 4). There were no apparent differences between the PBS and BAFASAL^®/inactivated BAFASAL^® treatments.