Table 2.
MICs and MBCs of B1OS, B1OS-L, and B1OS-D-L against six different microorganisms.
| Microorganisms | MICs/MBCs (µM) | MICs (μM) | |||
|---|---|---|---|---|---|
| B1OS | B1OS-L | B1OS-D-L | Norfloxacin a | ||
| Gram-positive | S. aureus (NCTC 6538) | 32/64 | 2/4 | 2/2 | NA |
| MRSA (NCTC 12493) | 64/128 | 4/8 | 4/4 | 6.26 | |
| E. faecalis (NCTC 12697) | 64/128 | 8/8 | 8/8 | 12.53 | |
| Gram-negative |
Escherichia coli (E. coli) (ATCC 8739) |
32/32 | 16/32 | 16/16 | NA |
|
Klebsiella pneumonia (K. pneumoniae) (ATCC 43816) |
64/128 | 64/64 | 32/32 | 6.26 | |
|
Pseudomonas aeruginosa (P. aeruginosa) (ATCC 9027) |
128/256 | 64/128 | 32/64 | NA | |
| HC50 b (µM) | 739.92 | 29.92 | 74.5 | NA | |
a From [17]; b HC50 is the concentration of the tested peptides that caused 50% haemolysis of the horse red blood cells; NA: Not applicable.