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Signs of clinical symptoms after SARS-CoV-2 virus challenge. Immunized ferrets (total n = 16, n = 4/PBS; n = 6/Ag only; n = 6/Ag + L-pampo) were intranasally challenged with 105.5 TCID50/mL SARS-CoV-2 (Korea Centers for Disease Control and Prevention, resource no. 43326) under anesthesia. The body weight (%) (A) and temperature (°C) (B) of ferrets on days 2, 4, 6, 8, and 10 after SARS-CoV-2 virus challenge. Data shown are mean ± SD.
