Table 1.

List of differentially expressed genes in the brains of mice treated with LPS, moPrP^res, moPrP^res/LPS, RML/LPS, and RML at 11 weeks of post-inoculation.

Gene Symbol	Gene Name	Fold Change	p-Value
Apoe	Apolipoprotein	−7.6	0.001
GbP4	Guanylate binding protein 4	−2.4	0.02
Grn	Granulin	−2.4	0.02
Sod1	Superoxide dismutase 1, soluble	−3.0	0.001
Bax	BCL2-associated X protein	−3.8	0.01
Ccl17	Chemokine (C-C motif) ligand 17	−1.5	0.04
Apoe	Apolipoprotein E	−2.8	0.02
Sprn	Shadow of prion protein	−2.2	0.01
C1qb	Complement component 1, q subcomponent, beta polypeptide	−1.7	0.005
Ifi27I2a	Interferon, alpha-inducible protein 27 like 2A	1.8	0.01
Nos2	Nitric oxide synthase 2, inducible	1.5	0.04
Tlr6	Toll-like receptor 6	2.1	0.001
Tlr3	Toll-like receptor 3	2.8	0.03
C4b	Complement component 4B (Chido blood group)	−1.9	0.07
Nos2	Nitric oxide synthase 2, inducible	1.4	0.08
Il1a	Interleukin 1 alpha	2.2	0.06
Il1f10	Interleukin 1 family, member 10	1.4	0.08
H2-T23	Histocompatibility 2, T region locus 23	1.8	0.03
C1qb	Complement component 1, q subcomponent, beta polypeptide	−1.8	0.09
Rtp4	Receptor transporter protein 4	−2.2	0.09
Sod1	Superoxide dismutase 1, soluble	−1.2	0.08
Ccl25	Chemokine (C-C motif) ligand 25	2.3	0.01
C1qb	Complement component 1, q subcomponent, beta polypeptide	−1.8	0.01
C4b	Complement component 4B (Chido blood group)	−2.2	0.08
Grn	Granulin	−1.4	0.05
Anp32a	Acidic (leucine-rich) nuclear phosphoprotein 32 family, member	−1.9	0.05
Sod1	Superoxide dismutase 1, soluble	−1.5	0.01
Bax	BCL2-associated X protein	−1.9	0.05