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. 2021 Sep 16;9(9):225. doi: 10.3390/toxics9090225

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© 2021 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).

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ORs (95% CIs) of MetS for rs1799964 T>C by metals. The logistic regression model was built as logit [p(MetS)/1 − p(MetS)] = β₀ + β_M,j M_j + β_SNP,1i SNP_1i + β_SNP,2i SNP_2i + β_c Covariates + ε. Adjusted covariates included age, gender, smoking, and drinking alcohol. The prevalence of MetS with metals was increased in Cu only (OR = 1.001, 95% CI: 1.000, 1.001). Genotype CC was associated with an elevated risk of MetS, and the OR was 2.14 (95% CI: 1.02, 4.53) adjusting for Co, OR = 2.16 (95% CI: 1.02, 4.57) adjusting for Cu, OR = 2.16 (95% CI: 1.03, 4.56) adjusting for Zn, OR = 2.40 (95% CI: 1.16, 4.98) adjusting for Se, OR = 2.26 (95% CI: 1.09, 4.68) adjusting for As, and OR = 2.30 (95% CI: 1.11, 4.77) adjusting for Pb.