Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2021 Aug 27;13(9):1708. doi: 10.3390/v13091708

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© 2021 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).

PMC Copyright notice

Change in body weight and survival of BALB/c mice challenged with six LD50 (LD99) pH1N1. Eight groups of mice (N = 8) either immunized with various MVA-vector based vaccines or with MVA vector (MVAtor) were challenged with pH1N1 3 weeks after the final immunization. Daily body weights were monitored up to 14 days post-challenge. Weight loss >20% body weight was scored as death. Vaccines that delivered NP combined (blended) with M2 or METRC had similar (15%) weight loss that improved over the monitored period. Despite substantial weight loss in recipients of single antigen MVA-M1 vaccine, M1 did not lessen the benefit of blended MVA M1 + MVA NP + MVA M2 or blended MVA M1 + MVA NP + MVA METRC vaccines.