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. 2021 Aug 8;44(10):1073–1083. doi: 10.1007/s40264-021-01098-4

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© The Author(s) 2021

Open AccessThis article is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License, which permits any non-commercial use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by-nc/4.0/.

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Fig. 2 — Patients’ responses to the question a ‘In your opinion, what are the benefits of reporting side effects directly to the national agency?’ (1 missing; 7 ‘none’; 21 other answers), and b ‘What are, in your opinion, the drawbacks of reporting side effects directly to the national agency?’ (112 ‘none’; 19 other answers). HCPs healthcare professionals, ADRs adverse drug reactions. Fig. 1A: ¹Overall P < 0.001. V = 0.27. The Netherlands significantly different from Croatia and the UK (both P < 0.001). ²Overall P = 0.011. V = 0.15. The UK significantly different from Croatia (P = 0.006) and the Netherlands (P = 0.005). ³Overall P = 0.004. V = 0.16. The UK significantly different from Croatia (P = 0.012) and the Netherlands (P = 0.001). Fig. 1B: ¹Overall P < 0.001. V = 0.25. The Netherlands significantly different from Croatia (P = 0.013) and the UK (P < 0.001)