Table 3.

Number (%) of patients who agreed or totally agreed per statement, starting with ‘I would report a side effect to the national agency …’, by country and p values for tests of differences across the countries

	Croatia	The Netherlands	UK	p Value
… if the side effect was severe	135 (99)	177 (95)	92 (92)	0.022 (V = 0.13) HR–NL: 0.024 NL–UK: 0.377 HR–UK: 0.004
… if the side effect influences my daily activities	130 (96)	165 (88)	90 (90)	0.068
… if the side effect is not mentioned in the PIL	122 (90)	163 (87)	85 (85)	0.551
… if I am worried about my own situation	130 (96)	165 (88)	86 (86)	0.028 (V = 0.13) HR–NL: 0.020 NL–UK: 0.586 HR–UK: 0.009
… if the side effect has not yet been resolved	127 (93)	154 (82)	84 (84)	0.013 (V = 0.14) HR–NL: 0.004 NL–UK: 0.724 HR–UK: 0.021
… if I am completely sure that the symptom is a side effect of my medicine	122 (90)	157 (84)	84 (84)	0.288
… if the side effect lasts for a relatively long period (for instance more than two/three days)	122 (90)	148 (79)	84 (84)	0.040 (V = 0.14) HR–NL: 0.011 NL–UK: 0.319 HR–UK: 0.193
… if the side effect is caused by a medicine prescribed by an HCP	120 (88)	155 (83)	85 (85)	0.411
… if I asked an HCP but he/she refused	115 (85)	160 (86)	86 (86)	0.947
… if the side effect is caused by a medicine that I use without a prescription from an HCP	94 (69)	88 (47)	61 (61)	< 0.001 (V = 0.20) HR–NL: < 0.001 NL–UK: 0.024 HR–UK: 0.194
… if I have purchased the medicine on the internet, not in the pharmacy	80 (59)	72 (39)	65 (65)	< 0.001 (V = 0.23) HR–NL: < 0.001 NL–UK: < 0.001 HR–UK: 0.335
… if completing the report takes only a few minutes of my time	105 (77)	128 (68)	79 (79)	0.083
… if the report will not be linked to my medical notes to which HCPs have access	80 (59)	113 (60)	30 (30)	< 0.001 (V = 0.25) HR–NL: 0.772 NL–UK: < 0.001 HR–UK: < 0.001

HCP healthcare professional, PIL patient information leaflet, HR Croatia, NL The Netherlands