Differences between Croatia, The Netherlands, and the UK in motives to report adverse drug reactions (ADRs) to the national agency were observed in 3 of the 23 motives and 4 of the 24 motives assessed in a survey study among healthcare professionals (HCPs) and patients, respectively.

For HCPs, differences across the countries in motives to report related to legal obligation, black triangle medicines, and the reporting of well-known ADRs.

For patients, differences across the countries in motives to report related to linkage between the report and the medical notes, complexity and time taken to report, medicines purchased on the internet, and the reporting of embarrassing ADRs.

Besides general ADR awareness and reporting strategies, country-specific strategies could be used to promote and increase the reporting of ADRs by HCPs and patients.