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. 2021 Sep 27;8:83. doi: 10.1186/s40634-021-00387-2

Table 3.

Clinical outcomes of studies utilising platelet-rich plasma

Study Type of Osteotomy Performed Intervention Number of Patients in Intervention Group Number of Patients in Control Group Number of Patients undergoing second-look Arthroscopy Pre-OP VAS Score Post-OP VAS score Pre-OP Kanamiya Grading Post-Op Kanamiya Grading Pre-OP Lysholm Score Post-OP Lysholm Score Pre-OP KOOS Score Post-OP KOOS Score
D’Elia et al, Revista Brasileira de Ortopedia 2015 [19] HTO PRP with BMAC 11 14 N.A Not Reported Not Reported Not Reported Not Reported Not Reported Not Reported Not Reported
Koh et al, Arthroscopy 2014 [21] HTO PRP with Adipose- derived MSC 21 23 44/44 patients at mean 19.8 months post-op

PRP (control) (n = 23) v

PRP-MSC (n = 21)

45.4 ± 7.1 v 44.3 ± 5.7

Not Reported

PRP (control) (n = 23) v

PRP-MSC (n = 21)

Grade I: 11 (47.8%) v 1 (4.8%)

Grade II: 11 (47.8%) v 9 (42.9%)

Grade III: 1 (4.3%) v 8 (38.1%)

Grade IV: 0 (0%) v 3 (14.3%)

PRP (control) (n = 23) v

PRP-MSC (n = 21)

56.7 ± 12.2 v 55.7 ± 11.5

PRP (control) (n = 23) v

PRP-MSC (n = 21)

At latest follow-up (mean 24.6 months (PRP) and 24.2 months (PRP-MSC))

80.6 ± 13.5 v 84.7 ± 16.2

Not Reported

PRP (control) (n = 23) v

PRP-MSC (n = 21)

At latest follow-up (mean 24.6 months (PRP) and 24.2 months (PRP-MSC)):

Pain subscale: 74.0 ± 5.7 v 81.2 ± 6.9

Symptom subscale: 75.4 ± 8.5 v 82.8 ± 7.2

VAS Visual Analogue Scale, KOOS Knee injury and Osteoarthritis Outcome Score, HTO High Tibial Osteotomy, MSCs Mesenchymal Stem Cells, PRP Platelet-Rich Plasma, BMAC Bone Marrow Aspirate Concentrate