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. Author manuscript; available in PMC: 2023 Oct 1.
Published in final edited form as: Semin Cancer Biol. 2021 Mar 27;85:4–32. doi: 10.1016/j.semcancer.2021.03.010

Figure 6. Mutant p53 regulates cell metabolism.

Figure 6.

Mtp53 is involved in the regulation of all critical metabolic pathways that WT p53 participates in. Major target genes regulated by mtp53 are shown in this figure. Blue arrows indicate regulatory effects (including both positive and negative effects). Black arrow indicates positive effects. Black perpendicular bar indicates negative effects. PKM2, pyruvate kinase isoform M2; PLA2G16, phospholipase A2, group XVI; ACP6, lysophosphatidic acid phosphatase type 6.