Table 1.
Baseline characteristics of all participants according to TyG index quartile.
| Characteristics | Total | TyG index | P-value | |||
|---|---|---|---|---|---|---|
| Quartile1 | Quartile2 | Quartile3 | Quartile4 | |||
| N | 2,035 | 509 | 508 | 509 | 509 | |
| Age (years), mean ± SD | 71.32 ± 6.75 | 71.70 ± 7.12 | 71.68 ± 7.01 | 71.13 ± 6.67 | 70.75 ± 6.15 | 0.069 |
| Female, n (%) | 806 (39.65%) | 244 (47.94%) | 214 (42.21%) | 185 (36.35%) | 163 (32.09%) | <0.001 |
| BMI (kg/m2), mean ± SD | 24.96 ± 3.39 | 23.55 ± 3.40 | 24.76 ± 3.27 | 25.40 ± 3.04 | 26.13 ± 3.29 | <0.001 |
| WC (cm), mean ± SD | 88.05 ± 9.22 | 84.46 ± 9.08 | 87.25 ± 9.38 | 89.38 ± 8.45 | 91.11 ± 8.61 | <0.001 |
| Heart rate, bpm | 71.87 ± 9.40 | 71.52 ± 9.92 | 71.36 ± 8.19 | 71.57 ± 8.85 | 73.02 ± 10.41 | 0.016 |
| SBP (mmHg), mean ± SD | 138.39 ± 19.43 | 135.07 ± 17.75 | 137.30 ± 19.15 | 137.64 ± 19.44 | 143.55 ± 20.33 | <0.001 |
| DBP (mmHg), mean ± SD | 77.28 ± 9.76 | 75.51 ± 9.50 | 76.44 ± 9.27 | 77.04 ± 9.38 | 80.10 ± 10.26 | <0.001 |
| FPG (mmol/L), mean ± SD | 6.04 ± 1.55 | 5.36 ± 0.68 | 5.71 ± 0.92 | 5.98 ± 1.04 | 7.10 ± 2.34 | <0.001 |
| Smoking status, n (%) | 0.913 | |||||
| Never | 1,488 (73.12%) | 363 (71.32%) | 372 (73.23%) | 373 (73.28%) | 380 (74.66%) | |
| Former | 340 (16.71%) | 87 (17.09%) | 85 (16.73%) | 86 (16.90%) | 82 (16.11%) | |
| Current | 207 (10.17%) | 59 (11.59%) | 51 (10.04%) | 50 (9.82%) | 47 (9.23%) | |
| Current drinking, n (%) | 506 (24.86%) | 143 (28.09%) | 134 (26.38%) | 108 (21.22%) | 121 (23.77%) | 0.060 |
| TC (mmol/L), mean ± SD | 5.26 ± 1.01 | 4.89 ± 0.94 | 5.22 ± 0.96 | 5.33 ± 0.95 | 5.61 ± 1.08 | <0.001 |
| HDL-C (mmol/L), mean ± SD | 1.42 ± 0.39 | 1.64 ± 0.39 | 1.48 ± 0.35 | 1.34 ± 0.30 | 1.22 ± 0.36 | <0.001 |
| LDL-C (mmol/L), mean ± SD | 3.21 ± 0.87 | 2.88 ± 0.77 | 3.24 ± 0.78 | 3.37 ± 0.79 | 3.36 ± 1.02 | <0.001 |
| TG (mmol/L), mean ± SD | 1.68 ± 0.93 | 0.89 ± 0.18 | 1.29 ± 0.20 | 1.72 ± 0.30 | 2.83 ± 1.11 | <0.001 |
| UA (umol/L), mean ± SD | 307.52 ± 87.42 | 297.52 ± 86.64 | 296.27 ± 85.04 | 312.38 ± 84.38 | 323.89 ± 90.76 | <0.001 |
| eGFR (mL/min/1.73 m2), mean ± SD | 80.17 ± 14.54 | 80.86 ± 13.72 | 79.69 ± 15.05 | 80.02 ± 14.58 | 80.09 ± 14.79 | 0.628 |
| TyG index | 8.86 ± 0.54 | 8.22 ± 0.22 | 8.65 ± 0.09 | 8.99 ± 0.11 | 9.58 ± 0.34 | <0.001 |
| baPWV | 1,998 ± 437 | 1,964 ± 450 | 1,976 ± 426 | 1,979 ± 406 | 2,074 ± 456 | <0.001 |
| CHD, n (%) | 468 (23.00%) | 101 (19.84%) | 125 (24.61%) | 129 (25.34%) | 113 (22.20%) | 0.147 |
| Hypertension, n (%) | 1,445 (71.29%) | 311 (61.46%) | 350 (69.31%) | 366 (72.05%) | 418 (82.28%) | <0.001 |
| Diabetes mellitus, n (%) | 477 (23.51%) | 56 (11.00%) | 83 (16.40%) | 115 (22.68%) | 223 (43.98%) | <0.001 |
| Anti-platelet agents, n (%) | 450 (22.16%) | 93 (18.31%) | 111 (21.89%) | 122 (24.02%) | 124 (24.41%) | 0.075 |
| Anti-hypertensive agents, n (%) | 902 (44.63%) | 182 (35.83%) | 221 (43.68%) | 244 (48.32%) | 255 (50.80%) | <0.001 |
| Hypoglycemic therapy, n (%) | 333 (16.41%) | 44 (8.64%) | 67 (13.24%) | 79 (15.58%) | 143 (28.21%) | <0.001 |
| Lipid-lowering therapy, n (%) | 212 (10.65%) | 37 (7.49%) | 49 (9.88%) | 56 (11.18%) | 70 (14.00%) | 0.009 |
| High baPWV | 508 (24.96%) | 111 (21.81%) | 117 (23.03%) | 121 (23.77%) | 159 (31.24%) | 0.002 |
| baPWV > 1,800 cm/s | 1,282 (63.00%) | 302 (59.33%) | 311 (61.22%) | 312 (61.30%) | 357 (70.14%) | 0.002 |
TyG, triglyceride glucose; SD, standard deviation; BMI, body mass index; WC, waist circumference; SBP, systolic blood pressure; DBP, diastolic blood pressure; FPG, fasting plasm glucose; TC, total cholesterol; HDL-C, high-density lipoprotein cholesterol; LDL-C, low-density lipoprotein cholesterol; TG, triglyceride; UA, uric acid; eGFR, estimated glomerular filtration rate; CHD, coronary heart disease; baPWV, brachial-ankle pulse wave velocity.