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. 2021 Sep 13;8:726943. doi: 10.3389/fcvm.2021.726943

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Copyright © 2021 Sharma, Zhao, Mentkowski, Sonkawade, Karthikeyan, Lang and Ying.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Images generated by PGGAN and CycleGAN. (A) MI image from original data. (B) MI image generated form PGGAN. (C) MI image shifted by kmeans after PGGAN generation. (D) MI image generated from CycleGAN. (E) MI image shifted by kmeans after CycleGAN generation. (F) Control image from original data. (G) Control image generated form PGGAN. (H) Control image image shifted by kmeans after PGGAN generation. (I) Control image generated from CycleGAN. (J) Control image shifted by kmeans after CycleGAN generation. Green circle in (D,E) is manually added so as to mark the abnormal morphology of the generated image.