Table 5.
Spearman rank correlations of PCBs (lipid adj.) and thyroid function of mothers and newborns at different BMI groups, in the EHF-Assaf-Harofeh-Ichilov birth cohort, Israel, 2013–2015, grouped by maternal pre-pregnancy BMI.
Maternal TSH | Maternal FT4 | Maternal | Maternal | NB T4 | ||
---|---|---|---|---|---|---|
Tg Ab | TPO Ab | |||||
BMI <19 ( N = 24) | ||||||
PCB 118 (ng/g lipids) | r | 0.412 | 0.287 | 0.341 | 0.477 | −0.237 |
p | 0.045# | 0.175 | 0.103 | 0.018# | 0.265 | |
PCB 138 (ng/g lipids) | r | 0.501 | 0.358 | 0.191 | 0.437 | −0.139 |
p | 0.013# | 0.086 | 0.370 | 0.033# | 0.517 | |
PCB 153 (ng/g lipids) | r | 0.518 | 0.305 | 0.178 | 0.401 | −0.177 |
p | 0.010# | 0.147 | 0.406 | 0.052 | 0.408 | |
PCB 180 (ng/g lipids) | r | 0.445 | 0.160 | 0.048 | 0.277 | −0.215 |
p | 0.030# | 0.454 | 0.823 | 0.191 | 0.313 | |
Sum PCBs (ng/g lipids) | r | 0.511 | 0.262 | 0.150 | 0.376 | −0.141 |
p | 0.011# | 0.216 | 0.483 | 0.070 | 0.510 | |
BMI 19–25 ( N = 88) | ||||||
PCB 118 (ng/g lipids) | r | 0.033 | −0.019 | −0.066 | −0.208 | 0.160 |
p | 0.760 | 0.860 | 0.542 | 0.052 | 0.136 | |
PCB 138 (ng/g lipids) | r | 0.002 | −0.038 | 0.048 | −0.057 | 0.192 |
p | 0.984 | 0.724 | 0.654 | 0.596 | 0.073 | |
PCB 153 (ng/g lipids) | r | −0.025 | 0.009 | 0.098 | −0.022 | 0.147 |
p | 0.820 | 0.934 | 0.363 | 0.842 | 0.170 | |
PCB 180 (ng/g lipids) | r | −0.019 | 0.034 | 0.112 | −0.021 | 0.076 |
p | 0.858 | 0.752 | 0.298 | 0.849 | 0.483 | |
Sum PCBs (ng/g lipids) | r | −0.009 | 0.009 | 0.073 | −0.052 | 0.146 |
p | 0.933 | 0.936 | 0.496 | 0.629 | 0.176 | |
BMI ≥ 25 ( N = 45) | ||||||
PCB 118 (ng/g lipids) | r | −0.224 | 0.079 | 0.134 | 0.179 | 0.275 |
p | 0.139 | 0.607 | 0.380 | 0.240 | 0.068 | |
PCB 138 (ng/g lipids) | r | −0.255 | 0.010 | 0.139 | 0.177 | 0.148 |
p | 0.091 | 0.947 | 0.361 | 0.245 | 0.331 | |
PCB 153 (ng/g lipids) | r | −0.265 | 0.039 | 0.088 | 0.116 | 0.182 |
p | 0.079 | 0.800 | 0.567 | 0.449 | 0.232 | |
PCB 180 (ng/g lipids) | r | −0.290 | 0.048 | 0.052 | 0.085 | 0.157 |
p | 0.053 | 0.754 | 0.732 | 0.579 | 0.302 | |
Sum PCBs (ng/g lipids) | r | −0.276 | 0.051 | 0.095 | 0.126 | 0.192 |
p | 0.066 | 0.738 | 0.535 | 0.411 | 0.206 |
r, Spearman's rho.
p, p-value.
p < 0.05.
TSH, Thyroid-stimulating hormone; FT4, Free Thyroxine; Tg Ab, Thyroglobulin autoantibodies; TPO Ab, Thyroid peroxidase antibodies; NB T4, newborn total thyroxine; PCB, polychlorinated biphenyl.
Bold: p-value < 0.05.