Table 2.
Case 1 and 2 outcomes at baseline, mid- and end Treatment and mid- and end Control.
| Outcome | Case | Baseline | Mid treatment | End treatment | Mid control | End control | Follow up |
|---|---|---|---|---|---|---|---|
| BFI | 1 | 5.67 | 1.56 | 1.00 | 6.78 | 6.33 | 7.00 |
| 2 | 4.33 | 5.89 | 2.33 | 2.78 | 3.89 | 4.56 | |
| ESS | 1 | 3.00 | 1.00 | 2.00 | 1.00 | 1.00 | 0.00 |
| 2 | 11.00 | 6.00 | 7.00 | 6.00 | 11.00 | 7.00 | |
| FSS | 1 | 5.22 | 2.22 | 2.11 | 3.67 | 5.78 | 5.67 |
| 2 | 2.33 | 3.56 | 2.00 | 2.11 | 3.11 | 3.33 | |
| HADS Depression | 1 | 5.00 | 2.00 | 3.00 | 4.00 | 2.00 | 5.00 |
| 2 | 6.00 | 3.00 | 3.00 | 4.00 | 4.00 | 6.00 | |
| ISI | 1 | 18.00 | 2.00 | 7.00 | 11.00 | 20.00 | 8.00 |
| 2 | 15.00 | 17.00 | 13.00 | 13.00 | 15.00 | 11.00 | |
| MEQ | 1 | 34.00 | 49.00 | 42.00 | 38.00 | 39.00 | 41.00 |
| 2 | 72.00 | 74.00 | 70.00 | 73.00 | 72.00 | 70.00 | |
| PSQI Global | 1 | 8.00 | 3.00 | 2.00 | 5.00 | 5.00 | 3.00 |
| 2 | 11.00 | 7.00 | 8.00 | 8.00 | 8.00 | 9.00 | |
| PVT Mean RT (ms) | 1 | 344.44 | – | – | – | – | – |
| 2 | 310.44 | 300.03 | 314.75 | 288.65 | 268.51 | – | |
| PVT Fastest 10% RT (ms) | 1 | 281.63 | – | – | – | – | – |
| 2 | 237.02 | 238.14 | 223.33 | 233.77 | 217.24 | – | |
| POPS (Objective) | 1 | −0.25 | 0.10 | −0.13 | 0.96 | −0.12 | 0.40 |
| 2 | 1.06 | 1.58 | 0.92 | 0.09 | 0.51 | 0.50 | |
| Sleep Onsetac | 1 | 22:43 | 00:48 | – | – | 00:14 | 01:09 |
| 2 | 21:39 | – | – | 20:52 | 21:42 | 21:37 | |
| Sleep Offsetac | 1 | 06:45 | 07:04 | – | – | 08:23 | 07:59 |
| 2 | 05:50 | – | – | 03:41 | 05:25 | 04:34 | |
| SOLbc | 1 | 10.59 | 60.90 | – | – | 6.69 | 7.17 |
| 2 | 5.11 | – | – | 8.00 | 7.94 | 10.21 | |
| WASObc | 1 | 46.53 | 11.97 | – | 21.78 | 19.36 | |
| 2 | 69.31 | – | – | 69.87 | 73.41 | 68.50 | |
| TSTbc | 1 | 435.48 | 364.00 | – | – | 468.36 | 470.42 |
| 2 | 421.85 | – | – | 339.60 | 389.35 | 347.86 | |
| Sleep efficiency (%)c | 1 | 87.45 | 74.68 | – | – | 90.89 | 90.78 |
| 2 | 83.74 | – | – | 75.76 | 81.27 | 79.09 |
BFI, Brief Fatigue Inventory; ESS, Epworth Sleepiness Scale; FSS, Fatigue Severity Scale; HADS, Hospital Anxiety and Depression Scale; ISI, Insomnia Severity Index; MEQ, Morningness Eveningness Questionnaire; PSQI, Pittsburgh Sleep Quality Index; POPS, Participation Objective Participation Subjective; PVT, Psychomotor Vigilance Task; SOL, Sleep onset latency; TST, Total sleep time; WASO, Wake after sleep onset. Some outcomes missing due to equipment failure.
Values represent real clock times, in 24 h time.
Outcome is in minutes.
Individual actigraphic sleep episodes were inspected and aligned with sleep diaries (see Supplementary Materials). Sleep outcome is derived from the average of data in mid- to end-treatment condition periods.