Table 1.
Demographic and Clinical Characteristics of 615 Included Patients with Alopecia Areata
| Variables | AA with AD (n = 76) | AA without AD (n = 539) | P-value |
|---|---|---|---|
| Sex, n (%) | 0.008* | ||
| ● Male | 15 (19.8) | 188 (35) | |
| ● Female | 61 (80.2) | 351 (65) | |
| Age at AA onset, year, mean (SD) | 37.9 (11.1) | 36.8 (10.7) | 0.618 |
| Age at AA onset, year, n (%) | 0.737 | ||
| ● < 18 | 5 (6.6) | 43 (8.0) | |
| ● 18–30 | 21 (27.6) | 173 (32.1) | |
| ● 31–45 | 18 (23.7) | 140 (26.0) | |
| ● 46–60 | 19 (25.0) | 108 (20.0) | |
| ● > 60 | 13 (17.1) | 75 (13.9) | |
| Duration of disease, month, median (IQR) | 8 (4.5–23.5) | 5 (3–11) | 0.09 |
| Duration of disease, n (%) | <0.001* | ||
| ● < 1 year | 43 (56.6) | 419 (77.8) | |
| ● > 1 year | 33 (43.4) | 120 (22.2) | |
| AA subtype, n (%) | 0.192 | ||
| ● Patch-type AA | 45 (59.2) | 380 (70.5) | |
| ● Multiple AA | 22 (28.9) | 109 (20.3) | |
| ● AT/AU | 8 (10.5) | 39 (7.2) | |
| ● Ophiasis | 1 (1.4) | 11 (2.0) | |
| Severity of AA (SALT score), n (%) | 0.181 | ||
| ● 0–25% | 51 (67.1) | 409 (75.9) | |
| ● 26–50% | 12 (15.8) | 48 (8.9) | |
| ● 51–75% | 5 (6.6) | 42 (7.8) | |
| ● 76–100% | 8 (10.5) | 40 (7.4) | |
| Body hair involvement, n (%) | 6 (8.2) | 16 (3.0) | 0.031* |
| Nail abnormalities, n (%) | 13 (17.1) | 41 (7.6) | 0.006* |
| Atopic diseases, n (%) | 30 (39.4) | 112 (20.7) | <0.001* |
| Family history of AA, n (%) | 2 (2.6) | 22 (4.1) | 0.541 |
| Family history of AD, n (%) | 6 (7.9) | 19 (3.5) | 0.071 |
Note: *Statistically significant.
Abbreviations: AA, alopecia areata; AD, autoimmune disease; AT/AU, alopecia totalis/alopecia universalis; IQR, interquartile range; SALT, Severity of Alopecia Tool; SD, standard deviation.