Table 2.
Spectrum and Prevalence of Comorbidities Observed in 615 Patients with Alopecia Areata
| Variables | AA with AD (n = 76) | AA without AD (n = 539) | P-value |
|---|---|---|---|
| Autoimmune conditions, n (%) | |||
| ● AITD | 42 (6.8) | - | - |
| ● Vitiligo | 15 (2.4) | - | - |
| ● SLE | 12 (2.0) | - | - |
| ● Psoriasis | 3 (0.5) | - | - |
| ● Rheumatoid arthritis | 2 (0.3) | - | - |
| ● Myasthenia gravis | 1 (0.2) | - | - |
| ● Systemic sclerosis | 1 (0.2) | - | - |
| Other comorbidities, n (%) | |||
| ● Atopic diseases | 30 (39.4) | 112 (20.7) | <0.001* |
| ● Iron deficiency anemia | 1 (1.3) | 6 (1.1) | 0.876 |
| ● Viral hepatitis B | 1 (1.3) | 5 (0.9) | 0.747 |
| ● HIV infection | 1 (1.3) | 6 (1.1) | 0.876 |
| ● Hypertension | 2 (1.5) | 10 (1.8) | 0.646 |
| ● Dyslipidemia | 1 (1.3) | 9 (1.6) | 0.309 |
| ● Type 2 diabetes mellitus | 3 (3.9) | 24 (4.4) | 0.841 |
| ● Malignancy | 2 (2.6) | 18 (3.3) | 0.744 |
| ● Psychiatric disorders | 0 | 4 (0.7) | 0.611 |
Note: *Statistically significant.
Abbreviations: AA, alopecia areata; AD, autoimmune disease; AITD, autoimmune thyroid disease; HIV, human immunodeficiency virus; SLE, systemic lupus erythematosus.