Figure 4. Summary of metabolic profile data. A color-coded schematic diagram is provided to summarize the metabolic data generated with Seahorse extracellular flux analyzer.

(A) summarizes the data of overnight rested (unstimulated) CD8⁺ T cells from all the different HIV cohorts compared with overnight-rested CD8⁺ T cells from HIV-uninfected donors. (B) summarizes the data of overnight anti-CD3/28 stimulated CD8⁺ T cells from all the different HIV cohorts against overnight anti-CD3/28–stimulated CD8⁺ T cells from HIV-uninfected donors. (C) summarizes the data of overnight-activated CD8⁺ T cells from all the different cohorts against overnight-rested autologous CD8⁺ T cells. The legend for the color code is on the top right corner of the figure.