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. 2021 Sep 13;15:742102. doi: 10.3389/fnins.2021.742102

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Copyright © 2021 Xiao, Zhao, Wang, Xue, Tan, Lan, Kuai, Wang, Li, Pan, Fu and Hu.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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The results of effective connectivity analysis of right amygdala subregions. (A) The subregions of the right amygdala: the centromedial amygdala (CM; yellow), laterobasal amygdala (LB; purple), and superficial amygdala (SF; red). (B–D) Represent the illustration of the abnormal effective connectivity of MDD in three different right amygdala subregions, respectively: CM, LB, and SF. The cool color arrows indicate significant decreased information flow of target brain regions in MDD. The gray indicates the specific abnormal brain regions, and the yellow/purple/red represents right CM/LB/SF, respectively. EC, effective connectivity; CM, centromedial amygdala; LB, basolateral amygdala; SF, superficial amygdala; PCUN, precuneus; IFGoperc, opercular part of inferior frontal gyrus; mSFG, medial superior frontal gyrus; PCC, posterior cingulate cortex; L, left hemisphere; R, right hemisphere.