TABLE 5.

Univariate and multivariate Cox proportional hazard models of DSS in breast cancer.

Variables	Univariate			Multivariate
	HR	95% CI	P-value	HR	95% CI	P-value
Age (years)
41–60	0.859	0.320–2.302	0.762
≥61	1.537	0.589–4.014	0.380
Subtype (PAM50)
LumB	1.228	0.438–3.446	0.696	1.065	0.361–3.140	0.909
HER2	2.481	0.809–7.611	0.112	1.288	0.410–4.046	0.665
Basal	3.981	1.934–8.196	0.000	4.709	2.117–10.475	0.000
Normal	2.658	1.190–5.937	0.017	2.451	1.031–5.827	0.042
Tumor size
T2	1.246	0.590–2.633	0.565	0.701	0.324–1.515	0.366
T3	2.001	0.789–5.071	0.144	1.087	0.401–2.948	0.870
T4	13.460	5.590–32.414	0.000	3.576	1.161–11.020	0.026
Lymph node status
N1	2.332	1.168–4.659	0.016	2.349	1.133–4.871	0.022
N2	3.814	1.630–8.927	0.002	3.245	1.303–8.078	0.011
N3	5.447	2.165–13.704	0.000	3.956	1.145–13.667	0.030
Metastasis status
M1	11.850	5.556–25.280	0.000	3.037	1.184–7.787	0.021
Risk group
High-risk	5.686	3.065–10.550	0.000	4.376	2.288–8.369	0.000

DSS, disease-specific survival; CI, confidence interval; HR, hazard ratio.