Indicators	AUC	95% CI	Cutoff	Sensitivity	Specificity	PPV	NPV	p
t-PSA	0.668	0.606–0.730	14.115	0.641	0.691	52.23%	78.50%	<0.000
PSAD	0.765	0.711–0.819	0.400	0.563	0.856	67.29%	78.19%	<0.000
PIRADS score	0.864	0.827–0.901	3	0.844	0.794	48.65%	92.81%	<0.000
T2WI score	0.848	0.809–0.887	3	0.789	0.790	46.87%	93.41%	<0.000
DWI score	0.859	0.821–0.897	2	0.828	0.778	42.67%	100.00%	<0.000
Total score	0.903	0.872–0.933	6	0.805	0.864	62.60%	93.05%	<0.000
Model 1	0.910	0.881–0.939	0.381	0.867	0.790	68.10%	91.83%	<0.000
Model 2	0.931	0.906–0.956	0.391	0.883	0.844	74.83%	93.18%	<0.000

tPSA, total PSA; PSAD, PSA density; PI-RADS score, prostate imaging reporting and date system score; T2WI score, T2WI score referring to PI-RADS v2; DWI score, DWI score referring to PI-RADS score; csPCa, clinical significant prostate cancer; Total score, T2WI score + DWI score. Model 1 = f/tPSA + PSAD + T2WI score. Model 2 = f/tPSA + PSAD + Total score; AUC, area under the curve; 95% CI, 95% confidence interval for AUC; Cutoff, best cutoff; PPV, positive predictive value; NPV, negative predictive value.