Table 5.

Post-hoc comparison of cortical surface area between patients with BD I and BD II and HCs

Cortical regions		BD I vs. HC	BD II vs. HC	BD I vs. BD II	Comparison
		p	p	p
Left hemisphere
	L Pars orbitalis	5.29×10-4	1.23×10-9	0.063	BD I & BD II<HC
	L Long insular gyrus	5.57×10-5	6.86×10-15	0.003	BD I & BD II<HC
Right hemisphere
	R Frontomarginal gyrus	0.018	7.36×10-6	0.141	BD II>HC
	R Subcentral gyrus	5.76×10-5	1.04×10-5	0.915	BD I & BD II<HC
	R Anterior cingulate gyrus	4.86×10-5	2.44×10-8	0.387	BD I & BD II<HC
	R Posterior mid-cingulate gyrus	2.77×10-4	1.38×10-6	0.541	BD I & BD II<HC
	R Ventral posterior cingulate gyrus	4.22×10-4	6.73×10-5	0.997	BD I & BD II>HC
	R Cuneus	1.43×10-4	6.11×10-6	0.845	BD I & BD II<HC
	R Pars opercularis	0.005	3.27×10-6	0.234	BD II<HC
	R Pars triangularis	1.71×10-4	1.30×10-5	0.921	BD I & BD II>HC
	R Middle frontal gyrus	4.31×10-4	1.01×10-4	0.944	BD I & BD II>HC
	R Superior frontal gyrus	3.41×10-4	6.35×10-5	0.970	BD I & BD II<HC
	R Long insular gyrus	0.977	1.12×10-5	6.57×10-4	BD II<BD I & HC
	R Superior occipital gyrus	0.109	1.01×10-5	0.037	BD II>HC
	R Lingual gyrus	2.80×10-4	1.33×10-4	0.816	BD I & BD II<HC
	R Parahippocampal gyrus	0.006	3.35×10-5	0.392	BD II>HC
	R Precuneus	4.58×10-4	3.65×10-4	0.746	BD I & BD II<HC
	R Straight gyrus	2.68×10-5	6.72×10-9	0.352	BD I & BD II<HC
	R Anterior transverse temporal gyrus	3.11×10-4	1.93×10-4	0.777	BD I & BD II>HC
	R Lateral superior temporal gyrus	8.15×10-5	3.95×10-6	0.885	BD I & BD II<HC
	R Planum temporale	1.08×10-3	3.10×10-4	0.943	BD II>HC

The general linear model (GLM) was adjusted for age, sex, educational level, and intracranial volume as covariates. Regions that remained significant after Bonferroni correction are listed: 76 regions of cortex, corrected p=(0.05/76)=6.58×10^-4. BD I, bipolar disorder type I; BD II, bipolar disorder type II; HC, healthy controls; SD, standard deviation