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. 2021 Sep 13;11:665231. doi: 10.3389/fonc.2021.665231

Table 4.

Sensitivity analysis for 1-, 2-, 3-, and 5-year OS rate, LRR, and DMR (CCRT vs. CCRT-CCT group).

Items Study omitted Estimate 95% CI
One-year OS rate Wu et al. (15) 0.588 0.467 0.741
Chen et al. (16) 0.667 0.538 0.826
Chen et al. (17) 0.625 0.501 0.780
Chen et al. (18) 0.651 0.528 0.802
Koh et al. (19) 0.649 0.522 0.805
Zhang et al. (20) 0.687 0.551 0.857
Combined 0.644 0.528 0.786
Two-year OS rate Wu et al. (15) 0.872 0.745 1.020
Chen et al. (16) 0.888 0.765 1.030
Chen et al. (17) 0.896 0.770 1.042
Koh et al. (19) 0.894 0.777 1.028
Combined 0.888 0.779 1.011
Three-year OS rate Wu et al. (15) 0.907 0.825 0.998
Chen et al. (16) 0.873 0.793 0.961
Chen et al. (17) 0.915 0.831 1.007
Chen et al. (18) 0.923 0.843 1.009
Koh et al. (19) 0.918 0.840 1.003
Zhang et al. (20) 0.941 0.858 1.032
Combined 0.914 0.840 0.995
Five-year OS rate Chen et al. (16) 0.902 0.810 1.004
Chen et al. (17) 0.971 0.893 1.056
Chen et al. (18) 0.994 0.912 1.078
Zhang et al. (20) 1.017 0.935 1.106
Combined 0.977 0.906 1.054
LRR Wu et al. (15) 0.965 0.717 1.299
Chen et al. (16) 0.660 0.424 1.028
Chen et al. (17) 0.965 0.712 1.306
Combined 0.899 0.686 1.179
DMR Wu et al. (15) 1.211 0.782 1.874
Chen et al. (16) 1.799 1.134 2.855
Chen et al. (17) 1.761 1.145 2.709
Combined 1.562 1.090 2.240

CCT, consolidation chemotherapy; CCRT, concurrent chemoradiotherapy; DMR, distant metastasis rate; LRR, local recurrence rate; OS, overall survival.