Skip to main content
. 2021 Sep 13;12:725511. doi: 10.3389/fpsyt.2021.725511

Table 3.

ROC analysis of serum YKL-40 in different types of dementia.

AUC 95% CI P Cut-off Sensitivity% 95% CI Specificity% 95% CI
t-tau
C vs. AD 0 0.845 0.7188–0.9712 0.0002 >338.4 75 53.13–88.81% 70 48.10–85.45%
C vs. VaD 0 0.7175 0.5561–0.8789 0.0186 >318.3 60 38.66–78.12% 55 34.21–74.18%
C vs. MxD 0 0.8825 0.7825–0.9825 <0.0001 >341.4 75 53.13–88.81% 70 48.10–85.45%
AD 0 vs. VaD 0 0.675 0.5060–0.8440 0.0583 <380.4 65 43.29–81.88% 65 43.29–81.88%
AD 0 vs. MxD 0 0.5975 0.4131–0.7819 0.2914 <394.4 55 34.21–74.18% 55 34.21–74.18%
VaD 0 vs. MxD 0 0.645 0.4675–0.8225 0.1167 >375.1 60 38.66–78.12% 60 38.66–78.12%
YKL-40
C vs. AD 0 0.8625 0.7510–0.9740 <0.0001 >106.3 85 63.96–94.76% 75 53.13–88.81%
C vs. VaD 0 0.8525 0.7352–0.9698 0.0001 >113.0 80 58.40–91.93% 80 58.40–91.93%
C vs. MxD 0 0.7975 0.6621–0.9329 0.0013 >103.9 70 48.10–85.45% 70 48.10–85.45%
AD 0 vs. VaD 0 0.5750 0.3926–0.7574 0.4171 >139.8 55 34.21–74.18% 50 29.93–70.07%
AD 0 vs. MxD 0 0.5775 0.3984–0.7566 0.4017 <130.7 50 29.93–70.07% 50 29.93–70.07%
VaD 0 vs. MxD 0 0.6200 0.4436–0.7964 0.1941 <137.9 55 34.21–74.18% 55 34.21–74.18%