Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2021 Sep 13;11:729799. doi: 10.3389/fonc.2021.729799

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

Copyright © 2021 Xie, Xu, Wei, An, Hao, Yu and Qiu

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

PMC Copyright notice

FHL2 expression is upregulated during Bzb-induced osteoblast differentiation of MM-MSCs. (A) Alizarin red staining was performed to show the osteoblast activity of differentiated MM-MSCs. (B) MM-MSCs were treated with indicated concentrations of Bzb for 7 days, and alkaline phosphatase index (API) was measured. (C) The protein level of FHL2 was evaluated by Western blot analysis after 24 h at indicated concentrations of Bzb. (D) FHL2 and osteoblast markers Runx2, ALP, and Col 1A1 mRNA expression was determined by quantitative RT-PCR at day 7. Results are expressed as mean ± SD (n = 3). **p < 0.01 vs. controls, ***p < 0.001 vs. controls.