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. 2021 Sep 21;16:2637–2651. doi: 10.2147/COPD.S313711

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© 2021 Stöber et al.

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Impact of clinical indicators on HRQoL: Linear relationship between change in FEV₁ and VAS (A) and CAT (B).

Notes: The estimated smooth functions of the relationship between FEV₁ and HRQoL are represented by the solid curves. The shaded areas indicate the 95% confidence intervals. Generalized additive models were adjusted for age, sex, smoking status, education, BMI, number of moderate and severe exacerbation, FEV₁ liter change, Charlson Comorbidity index, mMRC, and VAS/CAT baseline.