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. 2021 Sep 13;9:740635. doi: 10.3389/fbioe.2021.740635

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Copyright © 2021 Gong, Yu, Zhou, Dong, Yan, Zhang, Yan, Wang, Tan, Chen, Feng, Fu, Fu and Lu.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Macroscopic appearance, HE staining and gross measurements of dcECM hydrogel grafts after 8 weeks of in vivo transplantation. Grafts were harvested and compared at 8 weeks after transplantation. (A–H) Macroscopic appearance and HE staining of collagen I (Col-I) (A, E) and dcECM hydrogels at 1(B, F), 5 (C, G), and 10 (D, H) mg/ml grafts. (I, J) Gross analyses of weights (I) and volumes (J) from grafts. (K, L) Comparisons of collagen and GAG contents of grafts after 8 weeks of in vivo culture. Scale bars = 100 µm. Error bars showed means ± SD, *p < 0.05, n = 5.