Table 3.
Univariate and Multivariate Analyses of OS in EBSCC Patients
| Univariate Analyses | P-value | Multivariate Analyses | P-value | |
|---|---|---|---|---|
| HR (95% CI) | HR (95% CI) | |||
| Age (years) | 0.102 | |||
| ≤ 60 | 1.000 | |||
| > 60 | 0.543 (0.261–1.128) | |||
| Gender | 0.521 | |||
| Female | 1.000 | |||
| Male | 1.375 (0.520–3.634) | |||
| Tumor length (cm) | 0.028 | |||
| ≤ 3.0 | 1.000 | |||
| > 3.0 | 2.954 (1.126–7.748) | |||
| Tumor location | 0.350 | |||
| Upper/Middle | 1.000 | |||
| Lower | 0.679 (0.302–1.528) | |||
| Vessel invasion | 0.123 | |||
| Negative | 1.000 | |||
| Positive | 1.804 (0.853–3.814) | |||
| Smoking history | 0.240 | |||
| No | 1.000 | |||
| Yes | 1.579 (0.737–3.387) | |||
| Drinking history | 0.078 | |||
| No | 1.000 | |||
| Yes | 2.033 (0.924–4.475) | |||
| TNM stage | 0.010 | 0.002 | ||
| I | 1.000 | 1.000 | ||
| II–III | 2.811 (1.277–6.185) | 3.678 (1.609–8.407) | ||
| Surgery treatment | 0.115 | |||
| McKeown | 1.000 | |||
| Ivor Lewis | 0.558 (0.270–1.152) | |||
| Adjuvant treatment | 0.352 | |||
| No | 1.000 | |||
| Yes | 1.424 (0.677–2.995) | |||
| TC (mmol/L) | 0.857 | |||
| ≤ 4.400 | 1.000 | |||
| > 4.400 | 1.072 (0.500–2.298) | |||
| TG (mmol/L) | 0.033 | 0.006 | ||
| ≤ 1.325 | 1.000 | 1.000 | ||
| > 1.325 | 2.211 (1.066–4.586) | 2.906 (1.356–6.229) | ||
| HDL-C (mmol/L) | 0.109 | |||
| ≤ 1.220 | 1.000 | |||
| > 1.220 | 0.543 (0.257–1.145) | |||
| LDL-C (mmol/L) | 0.918 | |||
| ≤ 3.305 | 1.000 | |||
| > 3.305 | 1.042 (0.475–2.283) | |||
| APO A-I (g/L) | 0.014 | 0.014 | ||
| ≤ 1.305 | 1.000 | 1.000 | ||
| > 1.305 | 0.359 (0.158–0.814) | 0.352 (0.154–0.808) | ||
| APO B (g/L) | 0.536 | |||
| ≤ 1.010 | 1.000 | |||
| > 1.010 | 0.786 (0.367–1.685) | |||
| BMI (kg/m2) | 0.978 | |||
| ≤ 22.5 | 1.000 | |||
| > 22.5 | 1.010 (0.490–2.085) |
Note: P-values <0.05 were shown in bold.
Abbreviations: EBSCC, esophageal basaloid squamous cell carcinoma; TC, total cholesterol; TG, triglyceride; Apo A-I, apolipoprotein A-I; Apo B, apolipoprotein B; HDL-C, high-density lipoprotein-cholesterol; LDL-C, low-density lipoprotein-cholesterol; TNM, tumor, node, metastasis; CI, confidence interval; HR, hazard ratio; RFS, recurrence-free survival.