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. 2021 Sep 3;64(18):13622–13632. doi: 10.1021/acs.jmedchem.1c00995

Table 4. IC50 of (±)-1, (+)-1, and (−)-1 on Human 92-1 Cells at 48 h.

cmpd IC50 (μM)a ± SDb
(±)-1 5.5 ± 0.74
(+)-1 4.9 ± 0.58
(−)-1 4.4 ± 0.68
a

IC50 values represent absolute estimates calculated with GraphPad Prism 5 for Windows using a nonlinear fit transform sigmoidal dose–response (variable slope). IC50 values are averaged from multiple determinations (n = 3).

b

Values are expressed as mean ± SD of four independent experiments, each conducted in triplicate.