. 2021 Sep 1;64(18):13279–13298. doi: 10.1021/acs.jmedchem.1c00224

Table 2. Antagonist Properties of Compounds 8–11 at 5-HT₃ and 5-HT₆ Receptors^a^,^b.

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Percent inhibition of response to stimulation by 5-HT (contraction of guinea pig ileum) at the concentration of 3 μM induced by tested compounds (300 nM).

Percent inhibition of control agonist response at 10^–6 M; performed in duplicate in 1321N1 cells.

Table 2. Antagonist Properties of Compounds 8–11 at 5-HT3 and 5-HT6 Receptorsa,b.

Table 2. Antagonist Properties of Compounds 8–11 at 5-HT₃ and 5-HT₆ Receptors^a^,^b.