Skip to main content
. Author manuscript; available in PMC: 2021 Sep 27.
Published in final edited form as: Clin Sci (Lond). 2019 Dec 20;133(24):2449–2461. doi: 10.1042/CS20190876

Figure 5. Survival of SSWT and SSKcnj16−/− rats following pharmacological RAAS modulation.

Figure 5.

(A) Kaplan-Meier survival probability of SSWT rats on a LS LK diet (0.4% NaCl and 0.36% K+; N = 7), SSKcnj16−/− rats on a LS LK diet (0.4% NaCl and 0.36% K+; N = 17 total, 10 males and 7 females), and SSKcnj16−/− rats on a LS HK diet (0.4% NaCl and 1.41% K+; N = 6) were given IP injections of 50 mg/kg spironolactone daily for 10 days. (B) Kaplan-Meier survival probability of SSWT (N=3 males per ACEi and ARB treatment group) and SSKcnj16−/− rats (N=4 males per ACEi and ARB treatment group) injected with captopril or losartan (daily IP injections of 50 and 30 mg/kg, respectively) 8 days on a LS KL diet followed by 5 days on a HS LK diet.