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. 2020 Dec 14;11:100191. doi: 10.1016/j.bbih.2020.100191

Fig. 2.

Fig. 2

Anxiety-related behaviors of CD300f−/− female mice in different behavioral contexts. The total distance traveled in the OF was measured (meters) to evaluate female mice spontaneous ambulatory activity (n ​= ​12 WT and 12 CD300f−/−, 2.A) and the % of time spent in the center (n ​= ​12 WT and 12 CD300f−/−, 2.B), as well as the number of entries in the central zone (n ​= ​12 WT and 12 CD300f−/−, 2.C) of the OF, was used to evaluate anxious-like behavior. The number of entries in the open arms of the EPM (n ​= ​7 WT and 7 CD300f−/−, 2.D), the time spent in the open arms (n ​= ​7 WT and 7 CD300f−/−, 2.E) and closed arms (n ​= ​7 WT and 7 CD300f−/−, 2.F) of the EPM (calculated using the total time in the open arms or closed arms ​+ ​the total time in the closed arms as 100%) was used as indicative of anxiety. Data are represented as mean ​± ​S.E.M. Abbreviations: OF: Open Field; EPM: Elevated Plus Maze; WT: Wild-type mouse; CD300f−/−: CD300f knockout mouse.