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. 2021 Feb 22;13:100226. doi: 10.1016/j.bbih.2021.100226

Table 3.

Regression analyses for inflammatory markers at IPFU-2 predicting depression (BDI-II) at IPFU-3.

Inflammatory Markers
IL-6 (N ​= ​445)
CRP (N ​= ​457)
TNFα (N ​= ​391)
B SE B β p CI (95%) B SE B β p CI (95%) B SE B β p CI (95%)
Age 0.131 0.071 0.064 0.065 −0.008, 0.270 0.103 0.070 0.050 0.140 −0.034, 0.240 0.139 0.075 0.069 0.067 −0.009, 0.287
Gender −0.510 0.428 −0.043 0.234 −1.352, 0.332 −0.710 0.422 −0.060 0.094 −1.540, 0.120 −0.940 0.450 −0.081 0.037 −1.824, −0.056
Race 0.758 0.540 0.054 0.162 −0.305, 1.820 0.870 0.529 0.064 0.100 −0.169, 1.909 0.301 0.569 0.023 0.597 −0.819, 1.421
Ethnicity 0.827 1.278 0.022 0.518 −1.685, 3.339 1.032 1.268 0.027 0.416 −1.459, 3.523 1.660 1.413 0.043 0.241 −1.119, 4.439
SES −0.334 0.264 −0.047 0.207 −0.854, 0.185 −0.386 0.260 −0.055 0.138 −0.897, 0.125 −0.375 0.286 −0.054 0.191 −0.938, 0.188
BMI −0.041 0.033 −0.051 0.206 −0.105, 0.023 −0.066 0.034 −0.081 0.053 −0.132, 0.001 −0.022 0.033 −0.029 0.501 −0.088, 0.043
Physical Health −0.095 0.030 −0.148 0.002 −0.154, −0.035 −0.103 0.030 −0.162 0.001 −0.163, −0.044 −0.065 0.032 −0.104 0.043 −0.128, −0.002
MAP −0.013 0.015 −0.031 0370 −0.043, 0.016 −0.006 0.015 −0.016 0.654 −0.036, 0.022 −0.015 0.016 −0.036 0.336 −0.047, 0.016
Beta Blockers −0.571 0.512 −0.039 0.265 −1.577, 0.435 −0.378 0.503 −0.026 0.453 −1.367, 0.611 −0.575 0.550 −0.040 0.297 −1.656, 0.507
Calcium Blockers 0.354 0.523 0.024 0.499 −0.675, 1.383 0.553 0.510 0.039 0.279 −0.450, 1.555 0.591 0.542 0.042 0.276 −0.475, 1.658
Statins 0.751 0.454 0.060 0.099 −0.142, 1.644 1.005 0.445 0.082 0.028 0.131, 1.879 0.639 0.485 0.052 0.188 −0.314, 1.593
ACE Inhibitors −0.349 0.476 −0.028 0.464 −1.284, 0.587 −0.443 0.465 −0.036 0.340 −1.357, 0.470 −0.386 0.506 −0.031 0.445 −1.381, 0.608
Benzodiazepines 1.172 0.910 0.045 0.199 −0.617, 2.962 0.907 0.865 0.035 0.312 −0.853, 2.667 1.070 0.939 0.044 0.255 −0.776, 2.917
Hormones 0.305 0.719 0.014 0.672 −1.108, 1.717 0.592 0.710 0.028 0.405 −0.805, 1.988 −0.150 0.783 0.007 0.848 −1.690, 1.390
Aspirin −0.771 0.445 −0.063 0.084 −1.645, 0.104 −1.059 0.434 −0.087 0.015 −1.911, −0.207 −0.736 0.464 −0.062 0.114 −1.645, 0.178
Pain Medication −1.636 0.671 −0.090 0.015 −2.956, −0.316 −1.198 0.647 −0.068 0.065 −2.469, −0.073 −1.557 0.674 −0.090 0.021 −2.882, −0.232
NSAID 0.160 0.530 0.010 0.763 −0.882, 1.202 0.101 0.517 0.007 0.846 −0.915, 1.117 −0.408 0.549 −0.028 0.6458 −1.488, 0.672
Steroids 1.230 0.600 0.070 0.041 −0.052, 2.409 1.006 0.600 0.057 0.095 −0.174, 2.185 0.932 0.649 0.053 0.152 −0.345, 2.210
Anti-depressants 1.568 0.561 0.105 0.005 0.465, 2.671 1.401 0.550 0.094 0.011 0321, 2.481 1.999 0.597 0.136 <0.001 0.825, 3.172
Sleep −0.045 0.168 −0.010 0.790 −0.375, 0.285 −0.036 0.165 −0.008 0.82 −0.361, 0.289 −0.075 0.183 −0.016 0.681 −0.435, 0.285
Caffeine −0.167 0.122 −0.048 0.168 −0.407, 0.071 −0.099 0.122 −0.028 0.415 −0.339, 0.140 −0.082 0.134 −0.023 0.541 −0.344, 0.181
BDI-II at IPFPU-2 0.611 0.045 0.563 <0.001 0.522, 0.700 0.606 0.045 0.564 <0.001 0.518, 0.693 0.619 0.049 0.586 <0.001 0.523, 0.715
Inflammation at IPFU-2 1.758 0.835 0.080 0.036 0.116, 3.400 0.935 0.429 0.083 0.030 0.095, 1.778 1.049 1.041 0.039 0.314 −0.998, 3.097