Fig. 6.

CD3⁺ T and CD19⁺ B cell populations in BTBR and B6 mice. BTBR mice have significantly more T cells and fewer B cells than B6 mice. Representative flow cytometric analysis of B cells and T cells are shown for blood (A) and spleen (D) of B6 and BTBR mice. Frequency and number of CD3⁺ T cells and CD19⁺ B cells in the blood (B, C) and spleens (E, F) of B6 and BTBR mice (mean ​± ​SEM) are shown. Data are representative of three or four independent experiments with 4 pairs of mice in each experiment; significant differences between the two strains are indicated by ∗ ​= ​p ​< ​0.05, ∗∗ ​= ​p ​< ​0.01, ∗∗∗ ​= ​p ​< ​0.001.