Table 5.
Multivariate Model of Predictors for Requiring a Second Biopsy
| Model Parameter | Unadjusted OR (95% CI) | Adjusted OR (95% CI) |
|---|---|---|
| Sex | ||
| Female | 1 | 1 |
| Male | 0.99 (0.67–1.46) | 1.10 (0.73–1.64) |
| Age, y | ||
| <65 | 1 | 1 |
| 65–80 | 0.80 (0.53–1.21) | 0.76 (0.50–1.16) |
| >80 | 0.19 (0.06–0.56) | 0.20 (0.07–0.59) |
| Performance status | ||
| 0 | 1 | 1 |
| 1 | 0.83 (0.53–1.31) | 0.88 (0.55–1.40) |
| 2 | 0.58 (0.32–1.05) | 0.68 (0.36–1.27) |
| Stage | ||
| IIIB | 1 | 1 |
| IV | 1.08 (0.65–1.81) | 0.92 (0.53–1.59) |
| Sample method | ||
| EBUS-TBNA | 1 | 1 |
| Radiology-guided lung biopsy | 0.91 (0.54–1.53) | 0.96 (0.56–1.62) |
| Bronchoscopic biopsy | 0.65 (0.33–1.26) | 0.71 (0.36–1.39) |
| Thoracoscopic pleural biopsy, image-guided pleural biopsy, pleural aspiration | 1.99 (1.04–3.80) | 2.37 (1.20–4.70) |
| Mediastinoscopy, surgical lung resection, biopsy of other metastatic site, blood sample, and other | 1.11 (0.58–2.13) | 1.27 (0.64–2.50) |
CI, confidence interval; EBUS-TBNA, endobronchial ultrasound-guided transbronchial needle aspiration.