Table 2.

Cox Proportional Hazard Model of Overall Survival in the Development Cohort

Variable	β Coefficient	HR	95% CI	p Values
ECOG performance status: ≥2 vs. 0–1	0.82	2.27	1.79–2.87	<10–4
Disease stage: IV vs. non-IV	0.92	2.52	1.91–3.33	<10–4
Liver metastases: Yes vs. no	0.51	1.66	1.29–2.15	<0.01
NLR: ≥4 vs. <4	0.33	1.39	1.11–1.72	<10–4

HR, hazard ratio; NLR, neutrophils-to-lymphocytes ratio; ECOG, Eastern Cooperative Oncology Group; CI, confidence interval.