Table 1.
Table of Anti–PD-(L)1 Agents Undergoing Investigation by Tumor Type
Agent | Target | NSCLC | SCLC | Mesothelioma | TET | Total |
---|---|---|---|---|---|---|
ABBV-181 | PD-1 | 0 | 1 | 0 | 0 | 1 |
AK105 | PD-1 | 2 | 0 | 0 | 0 | 2 |
Atezolizumab | PD-L1 | 77 | 22 | 5 | 1 | 105 |
Avelumab | PD-L1 | 11 | 0 | 1 | 1 | 13 |
BI 754091 | PD-1 | 1 | 0 | 0 | 0 | 1 |
Camrelizumab | PD-1 | 20 | 3 | 0 | 0 | 23 |
Cemiplimab | PD-1 | 4 | 0 | 0 | 0 | 4 |
CS1001 | PD-L1 | 1 | 1 | 0 | 0 | 2 |
Durvalumab | PD-L1 | 87 | 18 | 4 | 0 | 109 |
HLX 10 | PD-1 | 2 | 1 | 0 | 0 | 3 |
KN046 | PD-L1/CTLA-4 | 3 | 0 | 0 | 1 | 4 |
M7824 | PD-L1/TGF-β | 4 | 1 | 0 | 1 | 6 |
MGA-012 | PD-1 | 1 | 0 | 0 | 0 | 1 |
Nivolumab | PD-1 | 118 | 18 | 12 | 2 | 150 |
Pembrolizumab | PD-1 | 158 | 13 | 16 | 6 | 193 |
Prolgolimab | PD-1 | 2 | 0 | 0 | 0 | 2 |
SHR-1316 | PD-L1 | 2 | 4 | 0 | 0 | 6 |
Sintilimab | PD-1 | 18 | 5 | 0 | 0 | 23 |
Spartalizumab | PD-1 | 4 | 0 | 0 | 0 | 4 |
Tislelizumab | PD-1 | 8 | 2 | 0 | 0 | 10 |
Toripalimab | PD-1 | 12 | 5 | 0 | 0 | 17 |
TQB2450 | PD-L1 | 4 | 2 | 0 | 0 | 6 |
TSR-042 | PD-1 | 1 | 0 | 0 | 0 | 1 |
PD-1, programmed cell death protein 1; PD-L1, programmed death-ligand 1; TET, thymic epithelial tumor; TGF-β, transforming growth factor-β.