Table 3.
Correlations between MST measures and both cognition and structural brain measures.
| MST measure | Cognition (partial
r) |
Structural brain measures
(r) |
|||
|---|---|---|---|---|---|
| Cross-sectional | Longitudinal | Deep GM volume | Cortical GM volume | WM lesion volume | |
| Leaf fraction | |||||
| Delta | 0.20^ | 0.19 | 0.35* | 0.12 | −0.33* |
| Theta | 0.18^ | <–0.01 | 0.27* | 0.12 | −0.32* |
| Alpha1 | 0.24* | 0.07 | 0.25* | 0.05 | −0.28* |
| Alpha2 | 0.20^ | 0.10 | 0.35* | 0.17^ | −0.37* |
| Beta | 0.22^ | 0.02 | 0.34* | 0.13 | −0.32* |
| Gamma | 0.19^ | 0.11 | 0.38* | 0.19^ | −0.36* |
| Betweenness centrality | |||||
| Delta | <0.01 | 0.07 | 0.01 | −0.09 | −0.05 |
| Theta | <–0.01 | −0.02 | 0.14 | 0.06 | −0.17 |
| Alpha1 | 0.06 | −0.04 | <–0.01 | −0.05 | <0.01 |
| Alpha2 | −0.08 | <0.01 | 0.06 | 0.05 | −0.14 |
| Beta | 0.05 | −0.02 | 0.08 | −0.04 | −0.13 |
| Gamma | −0.08 | 0.04 | 0.16 | 0.03 | −0.29* |
| Diameter | |||||
| Delta | −0.22^ | −0.22^ | −0.36* | −0.16 | 0.35* |
| Theta | −0.03 | 0.08 | −0.20^ | −0.03 | 0.25* |
| Alpha1 | −0.19^ | 0.04 | −0.13 | −0.06 | 0.15 |
| Alpha2 | −0.09 | −0.14 | −0.26* | −0.12 | 0.24* |
| Beta | −0.15 | 0.14 | −0.28* | −0.12 | 0.24* |
| Gamma | −0.11 | −0.02 | −0.27* | −0.14 | 0.33* |
| Tree hierarchy | |||||
| Delta | 0.20^ | 0.15 | 0.35* | 0.16^ | −0.31* |
| Theta | 0.20^ | <–0.01 | 0.23* | 0.11 | −0.28* |
| Alpha1 | 0.23* | 0.10 | 0.27* | 0.08 | −0.31* |
| Alpha2 | 0.27* | 0.11 | 0.37* | 0.17^ | −0.35* |
| Beta | 0.23* | 0.02 | 0.34* | 0.16 | −0.30* |
| Gamma | 0.25* | 0.10 | 0.35* | 0.21^ | −0.27* |
MST: minimum spanning tree; GM: gray matter; WM: white matter.
^
p < 0.05. *p < 0.008 (i.e. significant after correction for multiple comparisons). The partial correlations between cognition and the MST measures were corrected for age, education, sex, and for longitudinal cognition, also baseline cognition.