Table 5.
Association between change (pre to post) in cytokines and psychiatric symptoms using Spearman’s rank correlation test with 95% confidence intervals (CI).
| ΔMADRS-S |
ΔPSS |
ΔHADS-A |
|||||||
|---|---|---|---|---|---|---|---|---|---|
| n | Rho | 95% CI | n | Rho | 95% CI | n | Rho | 95% CI | |
| ΔTNF-α | 301 | −0.06 | [-0.17, 0.06] | 301 | −0.05 | [-0.17, 0.06] | 300 | −0.07 | [-0.18, 004] |
| ΔIL-6 | 301 | 0.00 | [-0.11, 0.13] | 301 | −0.01 | [-0.13, 0.10] | 300 | −0.06 | [-0.18, 0.04] |
| ΔIL-8 | 300 | 0.02 | [-0.10, 0.12] | 300 | 0.04 | [-0.07, 0.15] | 299 | 0.01 | [-0.11, 0.12] |
Note. Bootstrapping with 2000 iterations and bias corrected confidence intervals (CI) were used. MADRS-S = Montgomery Åsberg Depression Rating Scale Self-rated; PSS = Perceived Stress Scale; HADS-A = Hospital Anxiety and Depression Scale, Anxiety subscale; TNF-α = tumor necrosis factor alpha; IL-6 = interleukin-6; IL-8 = interleukin-8.