Table 1.
Clinical Characteristics of Kras Mutation in Patients With Nonsquamous NSCLC
| Characteristics | All Patients | G12C | Non-G12C | p |
|---|---|---|---|---|
| Total | 228 | 75 (32.9) | 153 (67.1) | |
| Age, median, y (range) | 66.0 (31.6–93.3) | 67.0 (45.5–93.0) | 65.5 (31.6–93.3) | 0.463a |
| Sex | 0.018 | |||
| Female | 69 | 15 (20.0) | 54 (35.3) | |
| Male | 159 | 60 (80.0) | 99 (64.7) | |
| Smoking status | <0.001 | |||
| Nonsmokers | 84 | 14 (18.7) | 70 (45.8) | |
| Smokers | 144 | 61 (81.3) | 83 (54.2) | |
| Stage | 0.376 | |||
| I–IIIa | 85 | 31 (41.3) | 54 (35.3) | |
| IIIb or IV | 143 | 44 (58.7) | 99 (64.7) | |
| Tumor | 0.132 | |||
| Adenocarcinoma | 203 | 71 (94.7) | 132 (86.3) | |
| Pleomorphic or sarcomatoid | 14 | 3 (4.0) | 11 (7.2) | |
| NSCLC-NOS | 11 | 1 (1.3) | 10 (6.5) |
Note: Values are given in number (%) unless indicated otherwise.
NOS, not otherwise specified.
a
By Mann-Whitney U test.