Table 2.
Logistic Regression for Complete Pathologic Response Among Surgical Patients
| Variable | OR | 95% Lower | 95% Upper | p Value |
|---|---|---|---|---|
| Radiation dose | ||||
| 45–54 Gy | Reference | |||
| 60–70 Gy | 1.200 | 0.991 | 1.454 | 0.062 |
| Age group, y | ||||
| <55 | Reference | |||
| 55–75 | 1.206 | 0.847 | 1.716 | 0.299 |
| >75 | 0.732 | 0.394 | 1.359 | 0.324 |
| Sex | ||||
| Male | Reference | |||
| Female | 0.854 | 0.707 | 1.032 | 0.102 |
| Race/ethnicity | ||||
| White non-Hispanic | Reference | |||
| Black | 1.239 | 0.661 | 2.324 | 0.504 |
| Hispanic | 0.705 | 0.201 | 2.468 | 0.584 |
| Other/unknown | 1.354 | 0.528 | 3.475 | 0.528 |
| Charlson-Deyo comorbidity index | ||||
| 0 | Reference | |||
| 1 | 1.354 | 1.016 | 1.806 | 0.039 |
| ≥2 | 1.137 | 0.773 | 1.671 | 0.515 |
| Year of diagnosis | ||||
| 2006–2009 | Reference | |||
| 2010–2012 | 1.422 | 1.066 | 1.897 | 0.017 |
| 2013–2016 | 1.417 | 1.069 | 1.879 | 0.016 |
| Clinical T stage | ||||
| 1 | Reference | |||
| 2 | 0.989 | 0.750 | 1.305 | 0.937 |
| 3 | 0.938 | 0.649 | 1.357 | 0.736 |
| 4 | 1.397 | 0.927 | 2.105 | 0.111 |
| Tumor location | ||||
| Main bronchus | — | |||
| Upper lobe | Reference | |||
| Middle lobe | 1.369 | 0.558 | 3.356 | 0.493 |
| Lower lobe | 1.034 | 0.582 | 1.839 | 0.909 |
| Overlapping lung | 0.746 | 0.201 | 2.767 | 0.661 |
| Lung NOS | 0.697 | 0.185 | 2.624 | 0.594 |
| Tumor laterality | ||||
| Right | Reference | |||
| Left | 1.153 | 0.951 | 1.399 | 0.148 |
| Facility type | ||||
| Community | 1.088 | 0.643 | 1.840 | 0.752 |
| Comprehensive | 0.954 | 0.676 | 1.346 | 0.785 |
| Academic | Reference | |||
| Histology | ||||
| Adenocarcinoma | 0.571 | 0.471 | 0.692 | <0.001 |
| Squamous | Reference | |||
| Tumor grade | ||||
| 1 | Reference | |||
| 2 | 0.700 | 0.446 | 1.100 | 0.122 |
| ≥3 | 1.117 | 0.750 | 1.663 | 0.586 |
| Unknown | 2.840 | 1.910 | 4.224 | <0.001 |
| Surgical resection type | ||||
| Segmentectomy | 1.029 | 0.221 | 4.789 | 0.971 |
| Lobectomy | Reference | |||
| Pneumonectomy | 0.861 | 0.374 | 1.984 | 0.726 |
NOS, not otherwise specified.