Table 2.
Association Between Histologic Classification and Radiologic Parameters
| Radiologic Features | Histologic Classification of Adenocarcinoma |
|||
|---|---|---|---|---|
| AIS | MIA | IA | p Value | |
| Location | ||||
| RUL | 0 | 2 | 13 | 0.19 |
| RML | 1 | 0 | 1 | |
| RLL | 0 | 1 | 5 | |
| RUL + RML + RLL | 0 | 0 | 1 | |
| RUL + RML | 0 | 0 | 1 | |
| LUL | 1 | 0 | 11 | |
| LLL | 0 | 0 | 10 | |
| Classification | ||||
| GGO | 1 | 0 | 1 | 0.020 |
| GGN | 0 | 0 | 8 | |
| Solid | 1 | 3 | 33 | |
| Margins of the nodule(s) | ||||
| Smooth | 1 | 0 | 1 | 0.018 |
| Spiculated | 0 | 1 | 30 | |
| Lobulated | 1 | 2 | 9 | |
| No margins | 0 | 0 | 2 | |
| Shape of the nodule(s) | ||||
| Round | 0 | 0 | 2 | 0.18 |
| Polygonal | 2 | 0 | 8 | |
| Irregular | 0 | 3 | 30 | |
| No margins | 0 | 0 | 2 | |
| Largest size of the nodule(s) (mm) | ||||
| Median (range) | 36 (28–44) | 16 (8–22) | 28 (4–250) | 0.28 |
| Largest size solid component (mm) | ||||
| Median (range) | 44 (44–44) | 16 (8–22) | 23 (4–250) | 0.36 |
| Pleural retraction | ||||
| Yes | 1 | 2 | 23 | 0.51 |
| No | 1 | 0 | 14 | |
| Air bronchogram | ||||
| Yes | 1 | 0 | 6 | 0.37 |
| No | 1 | 2 | 31 | |
| Cavities, bulla | ||||
| Yes | 1 | 0 | 6 | 0.37 |
| No | 1 | 2 | 31 | |
| Lymph-node involvement | ||||
| Yes | 0 | 0 | 11 | 0.43 |
| No | 2 | 2 | 25 | |
| Visual FDG uptakea | ||||
| No uptake | 1 | 0 | 0 | <0.001 |
| Faint | 0 | 0 | 8 | |
| Moderate | 1 | 1 | 3 | |
| Intense | 0 | 1 | 27 | |
RUL, right upper lobe; RML, right middle lobe; RLL, right lower lobe; LUL, left upper lobe; LLL, left lower lobe; GGO, ground-glass opacity; GGN, ground-glass nodule; SN, solid nodule; AIS, adenocarcinoma in situ; MIA, minimally invasive adenocarcinoma; IA, invasive adenocarcinoma; FDG, fluorodeoxyglucose.
a
FDG uptake was addressed as a semiquantitative evaluation.