Table 3.
Distribution of Pathologic Features for HR-CT and PET-CT
| Histologic parameters | Radiologic Classification of Nodules |
Margins on HR-CT |
Visual FDG Uptakea |
Size of the Solid Component on HR-CT (mm) |
||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| GGO | GGN | SN | p Value | SM | SP | LB | No M | p Value | NU | F | MOD | INT | p Value | Median (range) | p Value | |
| Histologic classification | ||||||||||||||||
| AIS | 1 | 0 | 1 | 0.003 | 1 | 0 | 1 | 0 | 0.024 | 1 | 0 | 1 | 0 | <0.001 | 44 (44–44) | 0.53 |
| MIA | 0 | 0 | 3 | 0 | 1 | 2 | 0 | 0 | 0 | 1 | 1 | 16 (8–22) | ||||
| IA with predominant lepidic component | 0 | 7 | 12 | 0 | 12 | 5 | 2 | 0 | 6 | 2 | 9 | 20 (5–160) | ||||
| IA without predominant lepidic pattern | 1 | 1 | 21 | 1 | 18 | 4 | 0 | 0 | 2 | 1 | 18 | 25 (4–250) | ||||
| Collapse | ||||||||||||||||
| Absent | 0 | 1 | 13 | 0.29 | 0 | 11 | 3 | 0 | 0.51 | 0 | 2 | 1 | 10 | 0.76 | 19 (4–250) | 0.53 |
| Present | 2 | 7 | 24 | 2 | 20 | 9 | 2 | 1 | 6 | 4 | 18 | 21 (5–160) | ||||
| Maximum size of invasive component (mm) | ||||||||||||||||
| ≤10 | 1 | 5 | 11 | 0.45 | 1 | 9 | 6 | 1 | 0.80 | 1 | 4 | 3 | 5 | 0.039 | 14 (4–160) | 0.003 |
| 11–20 | 0 | 1 | 6 | 0 | 5 | 2 | 0 | 0 | 2 | 2 | 2 | 13 (7–137) | ||||
| 21–30 | 0 | 2 | 8 | 0 | 8 | 1 | 1 | 0 | 2 | 0 | 8 | 24 (11–105) | ||||
| >30 | 1 | 0 | 12 | 1 | 9 | 3 | 0 | 0 | 0 | 0 | 13 | 45 (19–250) | ||||
IA has been split into two categories: with and without predominant lepidic pattern.
HR-CT, high-resolution computed tomography; PET-CT, positron emission tomography-computed tomography; GGO, ground-glass opacity; GGN, ground-glass nodule; SN, solid nodule; SM, smooth; SP, spiculated; LB, lobulated; No M, no margins; NU, no uptake; F, faint; MOD, moderate; INT, intense; AIS, adenocarcinoma in situ; MIA, minimally invasive adenocarcinoma; FDG, fluorodeoxyglucose; IA, Invasive adenocarcinoma.
a
FDG uptake was addressed as a semiquantitative evaluation.