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. 2020 Jun 8;5:100093. doi: 10.1016/j.bbih.2020.100093

Table 5.

Mean levels and group comparisons of plasma tryptophan, kynurenine and kynurenine:tryptophan ratio at Visit 1 and Visit 2.

Control
 CD
 UC
 P-value
Visit 1 Visit 2 Visit 1 Visit 2 Visit 1 Visit 2
Tryptophan 11923 ​± ​426.35 12122.91 ​± ​442.79 11002.09 ​± ​588.32 12563.59 ​± ​1003.27Ϯ 11452.74 ​± ​1226.7 9984.83 ​± ​828.9 0.413
Kynurenine 522.41 ​± ​23.90 527.67 ​± ​23.98 553.35 ​± ​43.03 645.16 ​± ​44.36 642.2 ​± ​68.22 542.16 ​± ​58.9 0.177
Kyn:Trp ratio 0.04 ​± ​0.0 0.04 ​± ​0.0 0.05 ​± ​0.0 0.06 ​± ​0.01 # 0.06 ​± ​0.00 ¥ 0.05 ​± ​0.1 0.023∗

CD, Crohn’s disease; UC, ulcerative colitis. p-value represents main group effect from repeated measures ANOVA across Visit 1 and 2; ∗p ​< ​0.05. Ϯp<0.05 vs control Visit 2; ¥p ​< ​0.05 vs control Visit 1; #p ​< ​0.001 vs control Visit 2. Data are mean ​± ​S.E.M.