Table 6.
Summary of correlations between averaged Visit 1 and 2 values for selective attention and response inhibition (Stroop Interference Effect), visuospatial memory performance (PAL Total Errors), physiological markers, anxiety, depression and disease activity.
Crohn’s Disease (CD) Group |
||
---|---|---|
Stroop Interference Effect (Mean of visit 1 & 2) | PAL Total Errors (Mean of visit 1 & 2) | |
Measure (Mean of visit 1 & 2) | ||
IL-6 | -.186 | -.032 |
IL-8 | -.207 | -.043 |
TNF-a | .368 | .154 |
L-Tryptophan | -.304 | -.086 |
L-Kynurenine | -.075 | -.243 |
Kyn:Trp Ratio | -.107 | -.171 |
CAR (AUCg) | .358 | .154 |
HADS-A (Anxiety) | -.022 | .038 |
HADS-D (Depression) | .132 | .221 |
PHQ-9 (Depression) | -.126 | .005 |
Disease Activity (HBI) | -.011 | .051 |
Disease Duration | .215 | -.022 |
WAIS IQ | -.082 | -.490 |
PAL, Paired Associate Learning; IL, interlukin; TNF-a, tumor necrosis factor-alpha; Trp:Kyn; kynurenine:tryptophan ratio; HADS-A/D, Hospital Anxiety and Depression Scale- Anxiety/Depression; HBI, Harvey Bradshaw Index; WAIS-R, Wechsler Adult Intelligence Scale-Revised.