Table 5.

Differentially expressed male offspring adrenal genes pertaining to steroidogenesis in pigs that were fed a low-quality protein diet and were from sows supplemented with AL, FO or CO then challenged with LPS or saline (n ​= ​4 for FO ​+ ​CON, n ​= ​3 for all other treatments).

Treatment Comparison	Gene	Description	Fold change	P-value
ALa+LPSb vs AL ​+ ​CONc	AIG1	Androgen-induced 1	−1.82	0.019
	HSDL2	Hydroxysteroid Dehydrogenase like 2	−1.77	0.011
	HSD11B1	11β Hydroxysteroid dehydrogenase type 1	−1.67	0.030
	AVPR1	Arginine vasopressin receptor 1	−1.62	0.015
	HSDL1	Hydroxysteroid Dehydrogenase like 1	1.24	0.039
FOd+LPS vs FO ​+ ​CON	MRAP2	Melanocortin 2 receptor accessory protein 2	−1.58	0.025
	CYP39A1	Cytochrome P450 39A1	−1.44	0.017
	CYP1a2	Cytochrome P450 1A2	1.21	0.039
	CYP4F2	Cytochrome P450 4F2	1.42	0.040
	CRHBP	Corticotropic releasing hormone binding protein	1.44	0.047
AL ​+ ​LPS vs COe+LPS	CYP2J2L	Cytochrome P450 2J2 like	1.52	0.035
AL ​+ ​CON vs CO ​+ ​CON	ADRA2A	Adrenoreceptor alpha 2A	−1.27	0.025
	ADRBK2	β-Adrenergic receptor kinase 2	1.40	0.008
	GLCCI1	Glucocorticoid induced 1	1.45	0.003
FO ​+ ​LPS vs CO ​+ ​LPS	CYP2J2L	Cytochrome P450 2J2 like	1.42	0.022
FO ​+ ​CON vs CO ​+ ​CON	ADRBK2	β-Adrenergic receptor kinase 2	1.21	0.023
	HSD11B2	11β Hydroxysteroid dehydrogenase type 2	1.71	0.023
AL ​+ ​LPS vs FO ​+ ​LPS	HSD11B2	11β Hydroxysteroid dehydrogenase type 2	−1.57	0.019
	HSDL2	Hydroxysteroid dehydrogenase like 2	−1.49	0.038
	HSDL1	Hydroxysteroid dehydrogenase like 1	1.22	0.041
	CYP1A1	Cytochrome P450 1A1	1.31	0.020
AL ​+ ​CON vs FO ​+ ​CON	HSD17B8	17β Hydroxysteroid Dehydrogenase type 8	−1.31	0.033

^aAL, microalgae.

^bLPS, lipopolysaccharide.

^cCON, saline control.

^dFO, fish oil.

^eCO, corn oil.