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. 2021 Apr 14;14:100254. doi: 10.1016/j.bbih.2021.100254

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© 2021 The Author(s)

This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).

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Fig. 2 — Significant between-group differences for pro-inflammatory IP-10 (A) and anti-inflammatory IL-1ra (B) markers from serum (with non-significant urine comparisons), and significant between-group differences for pro-inflammatory TNF-α (C), PDGF-bb (D), RANTES (E) and anti-inflammatory IL-10 (F) markers from urine (with non-significant serum comparisons) in people with multiple sclerosis and matched healthy control participants. Interferon-gamma and Granulocyte-macrophage colony-stimulating factor is not shown due to having minimal or undetectable levels from serum. IL-1ra, Interleukin 1 receptor antagonist; IL-10, Interleukin 10; IP-10, Interferon-gamma inducible protein 10; PDGF-bb, Platelet-derived growth factor 2 b subunits; RANTES, Regulated on activation normal T-cell expressed and secreted; and TNFα, Tumour necrosis factor-alpha. Concentrations are shown in fluorescence intensity values for serum and fluorescence intensity/creatinine values for urine.