Table 2.
Adjusted Means of Neurotoxicity Rating Scale of Dep and Non-Dep group.
| Depressed | 
Non-Depressed | 
Effect size of | 
p value | |
|---|---|---|---|---|
| (n = 94) | (n = 253) | ANCOVA | ||
| Age, years (mean ± SD) | 52 ± 9.25 | 49.46 ± 11.46 | - | .007** | 
| Gender | - | .002** | ||
| Female (%) | 51(58.62%) | 81(38.57%) | - | |
| - | ||||
| Education (years) | 8.54 ± 3.36 | 9.80 ± 4.41 | - | .018* | 
| Marriage, n (%) | .098 | |||
| Married | 66(75.86%) | 178(84.76%) | - | |
| Single/divorced | 21(24.1%) | 32(15.24%) | - | |
| Previous depression history(%) | 12(13.79%) | 3(1.43%) | - | < .001*** | 
| NRS scores (Adjusted mean ± SE) | ||||
| Week 02 | 5.43 ± 0.36 | 3.64 ± 0.23 | 0.29 | < .001*** | 
| Week 04 | 6.39 ± 0.42 | 3.58 ± 0.27 | 0.35 | < .001*** | 
| Week 08 | 6.96 ± 0.44 | 3.59 ± 0.28 | 0.41 | < .001*** | 
| Week 12 | 6.71 ± 0.43 | 3.59 ± 0.27 | 0.37 | < .001*** | 
| Week 16 | 6.50 ± 0.49 | 3.44 ± 0.31 | 0.29 | < .001*** | 
| Week 20 | 5.7 ± 0.47 | 3.40 ± 0.30 | 0.25 | < .001*** | 
| Week 24 | 5.35 ± 0.47 | 3.23 ± 0.30 | 0.26 | .0002*** | 
N, number; NRS, neurotoxicity rating scale; NRS somatic pain score, sum of the items 18, 19 and 20 of the NRS, which stand for generalized pain, arthralgia and other pain, respectively; SE, standard error. *indicates a statistical significance of p < .05. **indicates a statistical significance of p < .01. ***indicates a statistical significance of p < .001.